Formestane was originally used as an injectable for breast cancer patients, but due to its possible androgenic effects it has largely been replaced by non-steroidial AIs in the medical community. Most of its use is now is limited to the bodybuilding community since it is available as a legal dietary supplement for reducing estrogen and increasing testosterone production.

Although formestane can effectively reduce estrogen through oral consumption, its low oral bioavailability has lead to the development of several transdermal based products (which appear to offer higher efficacy at a lower dose).

Relative to 6-oxo and ATD, Formestane is a more potent aromatase inhibitor, which appears to effectively reduce natural estrogen levels by as much as 50% within several days (while higher doses may further suppress estrogen). Because of formestanes potent ability at reducing estrogen it will tend to reduce HDL levels, while increasing LDL levels, thus harming the cholesterol profile. For this reason, it is recommended to limit cycles of formestane to 8 weeks max.

Because formestane also has a strong affinity for the 5a-reductase enzyme it will reduce DHT levels in the body by effectively competing with testosterone for the 5a-reductase.

Formestane converts to the active androgen 4-hydroxytestosterone which has about half the anabolic potency, and about 25% of the androgenic potency as testosterone. This would suggest that fairly high doses of formestane (800-1000mg/day) could lead to some level of anabolic enhancement (although the amount required for this would surely lead to undesirably low estrogen levels).

Formestane is successfully used as a standalone during re-composition cycles to help reduce œbloat and fat storage. It can also be used as an anti-estrogen to counter aromatization of aromatizing steroids.

Supplement Facts

Serving Size: 1cc (1mL oral syringe)

Servings per container: 125

Amount Per Serving %DV*

Formestane 20mg**

(4-hydroxyandrostene-3, 17-dione)

*Daily Value

**Daily Value not established

Other Ingredients:

Liqua-Vade Technology [Distilled water, sorbitan monolaurate, exthoxylated sorbitan trioleate, ethoxylated mono and di-glycerides, medium chain triglycerides, sesame oil, grape spirits, dimethyl isosorbide, phospholipid complex (phosphatidylcholine, lysophosphatidylcholine), ethyl oleate, glyceryl triacetate, tocopheryl acetate, hydroxyproply methylcellulose], juice extract from purple carrot and hibiscus**, malt syrup, natural grape flavor, malic acid, sucralose, trisodium citrate, simethicone, potassium sorbate, sodium benzoate, citric acid, sucrose.

** For color
Used for food grade adhesive on syringe adapter Contains soy phosphatidylcholine

Recommended Use:

As a dietary supplement take one 1mL - 3mL dose, twice daily, 12 hours between each dose. Shake bottle well before each dose. Take with or without meals.

Do not use this product longer than 8 weeks without 8 weeks off between each cycle.

WARNING:

Product is not recommended for women, elderly, anyone under the age of 18 or anyone diagnosed with a serious health condition including but not limited to cancer, BPH, epilepsy, depression, diabetes, cardiovascular disease or high blood pressure. Always consult your physician before using this product with any over-the-counter or prescription medication.